Residency : IM Residency at Montefiore Med Ctr, NY
Thesis Advisor: Renee Tsolis, Ph.D.
Graduate Group: Microbiology
Current Position/Affiliations: Infectious Diseases Fellowship at U of Washington
Kerrinnes T, Young BM, Leon C, Roux CM, Tran L, Atluri VL, Winter MG, Tsolis RM. “Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity.” Antimicrob Agents Chemother. 2015 Nov.
Winter SE, Winter MG, Atluri VL, Poon V, Romão EL, Tsolis RM, Bäumler AJ. “The flagellar regular TviA reduces pyroptosis by Salmonella enterica serovar Typhi.” Infect Immun. 2015 Apr.
Silva TM, Mol JP, Winter MG, Atluri V, Xavier MN, Pires SF, Paixão TA, Andrade HM, Santos RL, Tsolis RM. “The predicted ABC transporter AbcEDCBA is required for type IV secretion system expression and lysosomal evasion by Brucella ovis.” PloS One. 2014 Dec 4.
Patra KP, Saito M, Atluri VL, Rolán HG, Young B, Kerrinnes T, Smits H, Ricaldi JN, Gotuzzo E, Gilman RH, Tsolis RM, Vinetz JM. “A protein-conjugate approach to develop a monoclonal antibody-based antigen detection test for the diagnosis of human brucellosis.” PloS Negl Trop Dis. 2014 Jun 5.
Xavier MN, Winter MG, Spees AM, den Hartigh AB, Nguyen K, Roux CM, Silva TM, Atluri VL, Kerrinnes T, Keestra AM, Monack DM, Luciw PA, Eigenheer RA, Bäumler AJ, Santos RL, Tsolis RM. “PPARy-mediated increase in glucose availability sustains chronic Brucella abortus infection in alternatively activated macrophages.” Cell Host Microbe. 2013 Aug 14.
Xavier MN, Winter MG, Spees AM, Nguyen K, Atluri VL, Silva TM, Bäumler AJ, Müller W, Santos RL, Tsolis RM. “CD4+ T cell-derived IL-10 promotes Brucella abortus persistence via modulation of macrophage function.” PloS Pathog. 2013.
Terwagne M, Ferooz J, Rolán HG, Sun YH, Atluri VL, Xavier MN, Franchi L, Núñez G, Legrand T, Flavell RA, De Bolle X, Letesson JJ, Tsolis RM. “Innate immune recognition of flagellin limits systemic persistence of Brucella.” Cell Microbiol. 2013 Jun.
Cannella AP, Lin JC, Liang L, Atluri VL, Gotuzzo E, Felgner PL, Tsolis RM, Vinetz JM. “Serial kinetics of the antibody response against the complete Brucella melitensis ORFeome in focal vertebral brucellosis.” J Clin Microbiol. 2012 Mar.
Atluri VL, Xavier MN, de Jong MF, den Hartigh AB, Tsolis RM. “Interactions of the human pathogenic Brucella species with their hosts.” Annu Rev Microbiol. 2011. Review
Paschos A, den Hartigh A, Smith MA, Atluri VL, Sivanesan D, Tsolis RM, Baron C. “An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation.” Infect Immun. 2011 Mar.
Liang L, Leng D, Burk C, Nakajima-Sasaki R, Kayala MA, Atluri VL, Pablo J, Unal B, Ficht TA, Gotuzzo E, Saito M, Morrow WJ, Liang X, Baldi P, Gilman RH, Vinetz JM, Tsolis RM, Felgner PL. “Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella meltiensis antigens.” PloS Negl Trop Dis. 2010 May 4.
V.L. Atluri, H.G. Rolan, M.N. Xavier, A.B. den Hartigh, L. Franchi, M. Winter, D. Monack, G. Núñez, K. Fitzgerald, and R. M. Tsolis. The Type IV Secretion System of Brucella spp. is required for activation of caspase-1. Brucellosis 2011 International Research Conference, Buenos Aires, Argentina (Sept 21-23, 2011).
V Atluri, M Winter, M Xavier, M de Jong, and R Tsolis. Activation of caspase-1 by Brucella melitensis is partially dependent on BopA. Toll2011, Lago di Garda, Italy (May 4-7, 2011).
V Atluri, M de Jong, R Tsolis. The role of BopA and BopB in Brucella pathogenesis. Conference: ASM 2010, San Diego, 2010.
Residency: Psychiatry Residency at Harvard Longwood- Beth Israel Deaconess Med Ctr, MA
Thesis Advisor: Dennis Matthews, Ph.D.
Graduate Group: Biomedical Engineering
Awasthi S, Izu LT, Mao Z, Jian Z, Landas T, Lerner A, Shimkunas R, Woldeyesus R, Bossuyt J, Wood B, Chen YJ, Matthews DL, Lieu DK, Chiamvimonvat N, Lam KS, Chen-Izu Y, Chan JW. “Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes.” Circ Res. 2016 Jan 22. Review.
Collier BB, Awasthi S, Lieu DK, Chan JW. “Non-linear optical flow cytometry using a scanned, Bessel bean light-sheet.” Sci Rep. 2015 May 29.
Awasthi S, Matthews DL, Li RA, Chiamvimonvat N, Lieu DK, Chan JW. “Label-free identification and characterization of human pluripotent stem cell-derived cardiomyocytes using second harmonic generation (SHG) microscopy.” J Biophotonics. 2012 Jan.
Wagner T, Shweta F, Murugadoss K, Awasthi S, Venkatakrishnan AJ, Bade S, Puranik A, Kang M, Pickering BW, O'Horo JC, Bauer PR, Razonable RR, Vergidis P, Temesgen Z, Rizza S, Mahmood M, Wilson WR, Challener D, Anand P, Liebers M, Doctor Z, Silvert E, Solomon H, Anand A, Barve R, Gores G, Williams AW, Morice WG 2nd, Halamka J, Badley A, Soundararajan V. “Augmented curation of clinical notes from a massive EHR system reveals symptoms of impending COVID-19 diagnosis.”
Sćepanović OR, Fitzmaurice M, Gardecki JA, Angheloiu GO, Awasthi S, Motz JT, Kramer JR, Dasari RR, Feld MS. “Detection of morphological markers of vulnerable atherosclerotic plaque using multimodal spectroscopy.”
Research Project: (1-2 sentences):
We are developing a label-free, non-invasive cell sorter capable of purifying stem cell-derived cardiomyocytes (SC-CMs) from the mixture of cells that results from a typical embryoid body or directed differentiation protocol. The technology is based off of second harmonic generation (SHG), a nonlinear optical process that occurs quite strongly in sarcomeric myosin. We are also using SHG to image the contractile dynamics of immature SC-CMs.
Presentations: Optics Within Life Sciences 2010 (Quebec City, QC, Canada). "Second
harmonic generation (SHG) microscopy of stem cell derived
SPIE Photonics West: BIOS 2011 (San Francisco, CA). "Characterization
of stem cell derived cardiomyocytes using second harmonic generation
Residency: Surgery – Preliminary, San Joaquin General Hospital
Alma Mater: University of California, Berkeley
Thesis Advisor: Jerry Powell (UC Davis), Shaun Coughlin (UCSF)
Graduate Group: BMCDB
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR. “Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia.” J Cell Biol. 2018 Mar 5;217(3):1097-1112.
Balouch E, “Role of Matriptase In Modulating Epithelial Integrity and Homeostasis” (unpublished doctoral thesis, University of California San Francisco, 2016)
Lee GM, Balouch E, Goetz DH, Lazic A, McKerrow JH, Craik CS. “Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy.” Biochemistry. 2012 Dec 18;51(50):10087-98.
The International Society for the Advancement of Spine Surgery (ISASS) 2020. San Juan, PR.
New York City Spinal Minimally Invasive Surgery Symposium (NYC-MISS) 2019. NY, NY.
Annual Research Day, San Joaquin General Hospital (2018)
BMCDB Graduate Group Retreat, Bodega Bay, CA Poster Presenter (2015)
Cardiovascular Research Institute, UCSF Retreat, Santa Cruz, CA Poster Presenter (2015)
Carolyn Zenith Black
Residency: Medicine Prelim at UCSF-Fresno
Alma Mater: University of Maryland, Baltimore County
Thesis Advisor: Lisa A. Miller
Graduate Group: BMCDB
Current Position/Affiliations: Pain Medicine & Rehab Residency at Harvard Spaulding Rehab Hospital, Chief Resident for AY 20-21
Black C, Gerriets JE, Fontaine JH, Harper RW, Kenyon NJ, Tablin F, Schelegle ES, Miller LA. Early Life Wildfire Smoke Exposure is Associated with Immune Dysregulation and Lung Function Decrements in Adolescence. Am J Respir Cell Mol Biol. 2017 Feb 16
Black C, Tesfaigzi Y, Bassein JA, Miller LA. “Wildfire smoke exposure and human health: Significant gaps in research for a growing public health issue.”
Residency: Med-Prelim/Opthalmology at U of Iowa
Alma Mater: University of California, Davis
Thesis Advisor: Marie Burns
Graduate Group: BMCDB
Peinado, G., Fortenbach, C.R., Naarendorp F., Gross O., Pugh E., Burns., M.E., “Bright flash response recovery of mammalian rods in vivo is rate limited by RGS9” The Journal of General Physiology (2017): jgp-201611692.
Fortenbach, C.R., et al. " Imaging Considerations in Suspected Intraocular Foreign Bodies” Advances in Ophthalmology & Visual System 4.4 (2016): 121-122
Fortenbach, C.R., et al. "Speeding rod recovery improves temporal resolution in the retina." Vision research 110 (2015): 57-67.
Modjtahedi, B.S., Fortenbach C.R., and A.C. Lorch. "Optic Nerve Head Avulsion: Clinical, Radiographic, and Sonographic Correlations." Ophthalmology 122.12 (2015): 2442.
Speeding rod recovery improves temporal resolution in the retina. Vision Res. 2015 May;110(Pt A):57-67. doi: 10.1016/j.visres.2015.02.011. Epub 2015 Mar 5.
Fortenbach CR, Modjtahedi BS, Maibach HI. “Role of physical chemical properties in drug relay into skin compartments.” Skin Pharmacology and Physiology. 2008;21(6):294-9.
Modjtahedi BS, Fortenbach CR, Marsano JG, Gandhi AM, Staab R, Maibach HI. “Guinea pig sensitization assays: An experimental comparison of three methods.” Cutaneous and ocular toxicology. 2011 Jun 1;30(2):129-37.
Ulu A, Appt SE, Morisseau C, Hwang SH, Jones PD, Rose TE, Dong H, Lango J, Yang J, Tsai HJ, Miyabe C, Fortenbach CR, Adams MR, Hammock BD. “Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys.” British journal of pharmacology. 2012 Mar;165(5):1401-12.
Mai AP, Fortenbach CR, Wibbenmeyer LA, Wang K, Shriver EM. “Preserving vision: rethinking burn patient monitoring to prevent orbital compartment syndrome.” Journal of Burn Care & Research. 2020 Apr 3.
Fortenbach CR, Modjtahedi BS. “Bilateral Enlargement of the Foveal Avascular Zone on Optical Coherence Tomography Angiography Associated With Cocaine Use.” JAMA Ophthalmology. 2020 Apr 16.
Fortenbach CR, Goldman E, Kishan AU, Mathew S, Modjtahedi BS, Morse LS. “The Role of Lipids and Lipid Metabolism in Age-Related Macular Degeneration.” In Handbook of Nutrition, Diet, and the Eye 2019 Jan 1 (pp. 47-71). Academic Press.
Quist TS, Fortenbach CR, Miller MA, Bettis DI, Topiramate-induced angle closure. EyeRounds.org. April 9, 2019. Available from http://EyeRounds.org/cases/283-topiramate-induced-angle-closure.htm
Walling A, Fortenbach CR, Larson S, Kemp P, Congenital Nasolacrimal Duct Obstruction. EyeRounds.org. May 13, 2020. Available from https://eyerounds.org/cases/296-congenital-nasolacrimal-duct-obstruction.htm
Yom KH, Mai AP, Fortenbach CR, Wibbenmeyer LA, Wang K, Shriver EM, Orbital Compartment Syndrome in a Burn Patient. EyeRounds.org. May 15, 2020. Available from https://webeye.ophth.uiowa.edu/eyeforum/cases/297-OCS-in-burn-patient.htm
Fortenbach CR, Peinado Allina G, Shores CM, Karlen SJ, Miller EB, Bishop H, Trimmer JS, Pugh EN, Burns ME. Physiological function and dysfunction of rods lacking Kv2.1, the principal K+ channel responsible for outward dark current. In review with Journal of General Physiology
Whitmore SS, Fortenbach CR, Cheng JL, Deluca AP, Crister DB, Stone EM, Han IC, Analysis of Retinal Sublayer Thicknesses and Rates of Thickness Change in ABCA4-Associated Stargardt Disease. In review with Scientific Reports
Fortenbach CR, Omar T, Maibach HI, Modjtahedi BS. Treatment of Ocular Rosacea. In Rosacea 2020 (ch 8). Springer Press.
Residency: IM Residency at Stanford
Alma Mater: UC Berkeley
Thesis Advisor: Martin Privalsky
Graduate Group: Biochemistry and Molecular Biology
Current Position/Affiliations: Assistant Professor of Medicine, Dept. of Hematology and Oncology, UC Davis; MD/PhD Steering Committee Member
Jonas BA, Greenberg PL. Best Pract Res Clin Haematol. 2015 Mar;28(1):3-13. doi: 10.1016/j.beha.2014.11.001. Epub 2014 Nov 11. PMID: 25659725 “MDS prognostic scoring systems – past, present, and future.”
Davis JR, Benjamin DJ, Jonas BA. J Investig Med. 2018 Dec;66(8):1088-1095. doi: 10.1136/jim-2018-000807. Epub 2018 Aug 19. PMID: 30127098 “New and emerging therapies for acute myeloid leukaemia.”
Jonas BA. Sci Transl Med. 2017 Jul 12;9(398):eaan8205. doi: 10.1126/scitranslmed.aan8205. PMID: 28701479 “On the origin of relapse in AML.”
Medeiros BC, Chan SM, Daver NG, Jonas BA, Pollyea DA. Am J Hematol. 2019 Jul;94(7):803-811. doi: 10.1002/ajh.25484. Epub 2019 May 1. PMID: 30945331 “Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia.”
Ho G, Li Q, Brunson A, Jonas BA, Wun T, Keegan THM. Am J Hematol. 2018 Nov;93(11):E370-E372. doi: 10.1002/ajh.25252. Epub 2018 Sep 26. PMID: 30105792 “Complications and early mortality in patients with acute promyelocytic leukemia treated in California.”
Malfatti MA, Buchholz BA, Enright HA, Stewart BJ, Ognibene TJ, McCartt AD, Loots GG, Zimmermann M, Scharadin TM, Cimino GD, Jonas BA, Pan CX, Bench G, Henderson PT, Turteltaub KW. Toxics. 2019 May 9;7(2):27. doi: 10.3390/toxics7020027. PMID: 31075884 “Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science.”
Jonas BA, Pollyea DA. Leukemia. 2019 Dec;33(12):2795-2804. doi: 10.1038/s41375-019-0612-8. Epub 2019 Oct 18. PMID: 31628431 “How we use venetoclax with hypomethylating agents for the treatment of newly diagnosed patients with acute myeloid leukemia.”
Wung W, Ananthakrishnan S, Jonas BA. J Investig Med High Impact Case Rep. 2018 Mar 14;6:2324709618764207. doi: 10.1177/2324709618764207. eCollection 2018 Jan-Dec. PMID: 29568782 “Proteinuria, Hypoalbuminemia, and Chronic Lymphocytic Leukemia: An Unusual Trio.”
Jonas BA. Sci Transl Med. 2017 Mar 8;9(380):eaam9861. doi: 10.1126/scitranslmed.aam9861. PMID: 28275157 “From MDS/AML to iPSC and back again.”
DiNardo CD, Pratz K, Pullarkat V, Jonas BA, Arellano M, Becker PS, Frankfurt O, Konopleva M, Wei AH, Kantarjian HM, Xu T, Hong WJ, Chyla B, Potluri J, Pollyea DA, Letai A. Blood. 2019 Jan 3;133(1):7-17. doi: 10.1182/blood-2018-08-868752. Epub 2018 Oct 25. PMID: 30361262 “Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia.”
Link to all publications; https://pubmed.ncbi.nlm.nih.gov/?term=Jonas%2C+Brian
Graduate Group: BMCDB
Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. “The Wnt effector transcription factor 7-like 2 positively regulates obligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.” J Neurosci. 2015 Mar 25.
Guo F, Lang J, Sohn J, Hammond E, Chang M, Pleasure D. “Canonical Wnt signaling in the obligodendroglial lineage—puzzles remain.” Glia. 2015 Oct. Review.
Sequerra EB, Cates S, Moreno M, Lang J, Orosco LA, Spencer K. “Endocannabinoid signaling alters internal programming of neuronal fate specification.” J Neurosci. 2013 Mar 27.
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, Guo F. “Adenomatous polyposis coli regulates obligodendroglial development.” J Neurosci. 2013 Feb 13.
Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. “PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum.” J Neurosci. 2012 Aug 29.Tomimatsu T, Lee SJ, Peña JP, Ross JM, Lang J, Longo LD. “Maternal caffeine administration and cerebral oxygenation in near-term fetal sheep.” Peprod Sci. 2007 Sep.
Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. J Neurosci. 2015 Mar 25;35(12):5007-22. doi: 10.1523/JNEUROSCI.4787-14.2015. “The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.”
Minakova E, Lang J, Medel-Matus JS, Gould GG, Reynolds A, Shin D, Mazarati A, Sankar R. PLoS One. 2019 Jan 10;14(1):e0210389. doi: 10.1371/journal.pone.0210389. eCollection 2019. “Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism.”
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, Guo F. J Neurosci. 2013 Feb 13;33(7):3113-30. doi: 10.1523/JNEUROSCI.3467-12.2013. “Adenomatous polyposis coli regulates oligodendroglial development.”
Sequerra EB, Cates S, Moreno M, Lang J, Orosco LA, Spencer K. J Neurosci. 2013 Mar 27;33(13):5437-8. doi: 10.1523/JNEUROSCI.0274-13.2013. “Endocannabinoid signaling alters internal programming of neuronal fate specification.”
Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. J Neurosci. 2012 Aug 29;32(35):12152-64. doi: 10.1523/JNEUROSCI.0628-12.2012. “PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum.”
Residency: Pediatrics Residency at U of Washington
Alma Mater: Princeton University
Thesis Advisor: Janine LaSalle, Ph.D.
Graduate group: BMCDB
Powell, Weston T., Rochelle L. Coulson, Florence K. Crary, Spencer S. Wong, Robert A. Ach, Peter Tsang, N. Alice Yamada, Dag H. Yasui, and Janine M. Lasalle. 2013. “A Prader-Willi Locus lncRNA Cloud Modulates Diurnal Genes and Energy Expenditure.” Human Molecular Genetics 22 (21) (November 1): 4318–28.
Powell, Weston T., Rochelle L. Coulson, Michael L. Gonzales, Florence K. Crary, Spencer S. Wong, Sarrita Adams, Robert A. Ach, et al. 2013. “R-Loop Formation at Snord116 Mediates Topotecan Inhibition of Ube3a-Antisense and Allele-Specific Chromatin Decondensation.” Proceedings of the National Academy of Sciences of the United States of America 110 (34) (August 20): 13938–43. Lasalle, Janine M., Weston T. Powell, and Dag H. Yasui. 2013. “Epigenetic Layers and Players Underlying Neurodevelopment.” Trends in Neurosciences 36 (8) (August): 460–70.
Powell, Weston T., and Janine M. LaSalle. 2013. “Imprinting in the CNS and Neurodevelopmental Disorders.” In Epigenetic Regulation in the Nervous System, edited by J. David Sweatt, Michael J. Meaney, Eric J. Nestler, and Schahram Akbarian, 267–279. Academic Press.
Meguro-Horike, Makiko, Dag H. Yasui, Weston Powell, Diane I. Schroeder, Mitsuo Oshimura, Janine M. Lasalle, and Shin-Ichi Horike. 2011. “Neuron-Specific Impairment of Inter-Chromosomal Pairing and Transcription in a Novel Model of Human 15q-Duplication Syndrome.” Human Molecular Genetics 20 (19): 3798–3810.
Powell WT, LaSalle JM. “Epigenetic mechanisms in dilurnal cycles of metabolism and neurodevelopment.” Hum Mol Genet. 2015 Oct 15.
Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM. “R-Loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.” Proc Natl Acad Sci U.S.A. 2013 Aug 20.
Audrea M. Burns, Kate Ackerman, Satid Thammasitboon, Caroline Rassbach, Mark A. Ward, Rebecca Blankenburg, Catherine S. Forster, Heather McPhillips, Tara Wenger, Weston T. Powell, Melvin B. Heyman, Michael Hogarty, Debra Boyer, Margaret Hostetter, Pnina Weiss, Suong Nguyen, Donald Williams Parsons, Daniel J. Moore, Bobbi Byrne, Anthony French, Jordan S. Orange. “Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency.” Pediatric Research. 2020 Mar 16.
Rochelle L. Coulson, Weston T. Powell, Dag H. Yasui, Gayathri Dileep, James Resnick, Janine M. LaSalle. “Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN.” Human Molecular Genetics. 2018 Dec 1; 27(23):4051-4060.
Powell, Weston T., Robyn A. Borghese, Karen M. Kalanetra, Majid Mirmiran, David A. Mills, Mark A. Underwood. “Probiotic Administration in Infants with Gastroschisis: A Pilot Randomized Placebo-Controlled Trial.” Journal of Pediatric Gastroenterology and Nutrition. 2015 Nov 3.
Christiaen, Lionel, Brad Davidson, Takeshi Kawashima, Weston T. Powell, Hector Nolla, Karen Vranizan, and Michael Levine. 2008. “The Transcription/migration Interface in Heart Precursors of Ciona Intestinalis.” Science 320 (5881): 1349–1352.
Fellowships and Awards: 2011-2013
NINDS Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in MD-PhD programs (F31). Award F31NS073164. March 2013 2013 Max Kleiber Graduate Research Prize. Awarded annually in recognition of the most outstanding dissertation in the areas of nutrition and metabolism. November 2012 2012 ASHG/Charles J. Epstein Trainee Award for Excellence in Human Genetics Research. Awarded at the annual ASHG meeting for excellence in research presented.
Thesis Advisor: John M. Boone, Ph.D.
Graduate Group: Biomedical Engineering
N. D. Prionas, S. Y. Huang and J. M. Boone, "Experimentally determined spectral optimization for dedicated breast computed tomography," Med Phys 38, 646-655 (2011).
N. D. Prionas, K. K. Lindfors, S. Ray, S. Y. Huang, L. A. Beckett, W. L. Monsky and J. M. Boone, "Contrast-enhanced dedicated breast CT: initial clinical experience," Radiology 256, 714-723 (2010).
N. D. Prionas, S. Ray and J. M. Boone, "Volume assessment accuracy in computed tomography: a phantom study," J Appl Clin Med Phys 11, 3037 (2010).
N. D. Prionas, M. A. Gillen and J. M. Boone, "Longitudinal volume analysis from computed tomography: Reproducibility using adrenal glands as surrogate tumors," J Med Phys 35, 174-180 (2010).
S. Y. Huang, J. M. Boone, K. Yang, N. J. Packard, S. E. McKenney, N. D. Prionas, K. K. Lindfors and M. J. Yaffe, "The characterization of breast anatomical metrics using dedicated breast CT," Medical Physics 38, 2180-2191 (2011).
Aminololama-Shakeri S, Abbey CK, Gazi P, Prionas ND, Nosratieh A, Li CS, Boone JM, Lindfors KK. “Differentiation of ductal carcinoma in-situ from benign micro-calcifications by dedicated breast computed tomography.” Eur J Radiol. 2016 Jan.
Prionas ND, Burkett GW, McKenney SE, Chen L, Stern RL, Boone JM. “Development of a patient-specific two-compartment anthropomorphic breast phantom.” Phys Med Biol. 2012 Jul 7.
Katzberg RW, Monsky WL, Prionas ND, Sidhar V, Southard J, Carlson J, Boone JM, Lin TC, Li CS. “Persistent CT nephrograms following cardiac catheterization and intervention: initial observations.” Insights Imaging. 2012 Feb.
Prionas ND, McKenney SE, Stern RL, Boone JM. “Kilovoltage rotational external beam radiotherapy on a breast computed tomography platform: a feasibility study.” Int J Radiat Oncol Biol Phys. 2012 Oct 1.
Huang SY, Boone JM, Yang K, Packard NJ, McKenney SE, Prionas ND, Lindfors KK, Yaffe MJ. “The characterization of breast anatomical metrics using dedicated breast CT.” Med Phys. 2011 Apr.
Thesis Advisor: William J. Murphy
Graduate Group: Immunology
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. “Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity.” Immunity. 2015 Aug 18.
Alvarez M, Bouchlaka MN, Sckisel GD, Sungur CM, Chen M, Murphy WJ. “Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells.” J Immunol. 2014 Aug 15.
Sungur CM, Murphy WJ. “Positive and negative regulation by NK cells in cancer.” Crit Rev Oncog. 2014. Review.
Sungur CM, Murphy WJ. “Utilization of mouse models to decipher natural killer cell biology and potential clinical applications.” Hematology Am Soc Hematol Educ Program. 2013. Review.
Barao I, Wright PW, Sungur CM, Anderson SK, Redelman D, Murphy WJ. “Differential expression of the Ly49G (B6) , but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation.” Biol Blood Marrow Transplant. 2013 Oct.
Residency: Medicine-Preliminary at California Pacific Med Ctr
Alma Mater: Stanford University
Thesis Advisor: Katherine Ferrara
Graduate Group: Biomedical Engineering
Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci S, Watson KD, Wong AW, Monjazeb A, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW. Incorporation of image-guided thermal ablation into immunotherapy protocols: priming is key to effective therapy. Accepted by JCI Insight. Feb 2017.
Shapiro G*, Wong AW*, Bez M, Yang F, Tam S, Even L, Sheyn D, Ben-David S, Tawackoli W, Pelled G, Ferrara KW, Gazit D. Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation. J Control Release. 2015;(15)30253-4. *Co-First Author
Wong AW, Fite BZ, Liu Y, Kheirolomoom A, Seo JW, Watson KD, Mahakian LM, Tam SM, Zhang H, Foiret J, Borowsky AD, Ferrara KW. Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models. J Clin Invest. 2016;126(1)99-111.
Fite BZ, Wong AW, Liu Y, Mahakian LM, Tam SM, Aina O, Hubbard NE, Borowsky AD, Cardiff RD, Dumont E, Ferrara KW. Magnetic Resonance Imaging Assessment of Effective Ablated Volume following High Intensity Focused Ultrasound. PLOS One. 2015;(10)3.
Wong AW, Ormsby E, Zhang H, Seo JW, Mahakian LM, Caskey CF, Ferrara KW. A comparison of image contrast with (64)Cu-labeled long circulating liposomes and (18)F-FDG in a murine model of mammary carcinoma. Am J Nucl Med Mol Imaging. 2013;3(1):32-43. Epub 2013 Jan 5.
Cheng T, Maddox NC, Wong AW, Rahnama R, Kuo AC. Comparison of gene expression patterns in articular cartilage and dedifferentiated articular chondrocytes. J Orthop Res. 2012 Feb; 30(2):234-45.
Fite BZ, Wong A, Liu Y, Mahakian LM, Tam SM, Aina O, Hubbard NE, Borowsky A, Cardiff RD, Dumont E, Ferrara KW. “Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound.”
Shapiro G, Wong AW, Bez M, Yang F, Tam S, Even L, Sheyn D, Ben-David S, Tawackoli W, Pelled G, Ferrara KW, Gazit D. “Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation.”
Wong AW, Fite BZ, Liu Y, Kheirolomoom A, Seo JW, Watson KD, Mahakian LM, Tam SM, Zhang H, Foiret J, Borowsky AD, Ferrara KW. “Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models.”
Wong AW, Ormsby E, Zhang H, Seo JW, Mahakian LM, Caskey CF, Ferrara KW. “A comparison of image contrast with (64)Cu-labeled long circulating liposomes and (18)F-FDG in a murine model of mammary carcinoma.”
Wong AW, Kheirolomoom A, Liu Y, Foiret J, Fite B, Ingham E, Ferrara KW. Achieving a durable response by combining chemotherapy with focused ultrasound in mouse models of cancer. Oral presentation at IEEE International Ultrasonics Symposium, October 2015.
Wong A, Ormsby E, Zhang H, Seo JW, Ferrara K. 64Cu-Liposomes vs. [18F]Flurodeoxyglucose as positron emission tomography contrast agents in the murine MET-1 tumor model. Poster presentation at NIBIB Trainee Grantees Meeting, June 2014.
Wong AW, Watson KD, Fite BZ, Liu Y, Seo JW, Mahakian LM, Tam SM, Kheirolomoom A, Ferrara KW. Overcoming accelerated blood clearance of Cu-doxorubicin nanoparticles with MR guided focused ultrasound thermal ablation. Oral presentation at 31st Annual Meeting of Society for Thermal Medicine, May 2014. Awarded New Investigator Travel Award.
Wong AW, Watson KD, Fite BZ, Liu Y, Seo JW, Mahakian LM, Tam SM, Kheirolomoom A, Ferrara KW. Enhanced accumulation of Cu-doxorubicin nanoparticles with MR guided focused ultrasound thermal ablation. Oral presentation at 14th Annual Meeting of the International Society of Therapeutic Ultrasound, April 2014. Awarded Nadine Barrie Smith Student Award for Best Overall Student Paper or Poster.
Wong AW, Watson KD, Fite BZ, Ingham E, Liu Y, Ferrara KW. Ultrasound Chemoimmunotherapy of Breast Cancer in Mice. Oral presentation at Interdisciplinary Graduate and Professional Symposium. April 2013; Davis, CA. Awarded “People’s Choice”.
Wong A, Ormsby E, Zhang H, Seo JW, Ferrara K. 64Cu-Liposomes vs. [18F]Flurodeoxyglucose as positron emission tomography contrast agents in the murine MET-1 tumor model. Oral presentation at Western Student Medical Research Forum. J Invest Med, 60(1):126-248, January 2012.